Synthesis of Polyamides from D-Glutamic Acid Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis of D-@-Glutamine from P-Glutamic Acid by Glutamine Synthetase*
In contrast to fi-glutamine and @glutamylhydroxamic acid, fl-glutamic acid does not possess an asymmetric carbon atom, but has, according to the nomenclature of Schwartz and Carter (2), a meso carbon atom. The present experiments were designed to determine whether glutamine synthetase distinguishes between the carboxyl groups of P-glutamic acid. It is noteworthy in this connection that the enzy...
متن کاملSynthesis and characterization of new polyamides derived from alanine and valine derivatives
UNLABELLED BACKGROUND Many efforts have been recently devoted to design, investigate and synthesize biocompatible, biodegradable polymers for applications in medicine for either the fabrication of biodegradable devices or as drug delivery systems. Many of them consist of condensation of polymers having incorporated peptide linkages susceptible to enzymatic cleavage. Polyamides (PAs) containi...
متن کاملA New Synthesis of Glutamic Acid*
Glutamic acid has been prepared previously by the racemization (1) of the natural dextro form and by three synthetic methods. The first synthesis, that by Wolff (2) in 1890, is principally of theoretical interest as it involves the preparation of six intermediate substances starting with levulinic acid and the yield of final product is not given. In 1925 Knoop and Oesterlin (3) obtained 1.1 gm....
متن کامل[A new synthesis of glutamic acid].
Glutamic acid has been prepared previously by the racemization (1) of the natural dextro form and by three synthetic methods. The first synthesis, that by Wolff (2) in 1890, is principally of theoretical interest as it involves the preparation of six intermediate substances starting with levulinic acid and the yield of final product is not given. In 1925 Knoop and Oesterlin (3) obtained 1.1 gm....
متن کاملStereocontrolled synthesis of 5-azaspiro[2.3]hexane derivatives as conformationally “frozen” analogues of L-glutamic acid
Several strategies aimed to "freeze" natural amino acids into more constrained analogues have been developed with the aim of enhancing in vitro potency/selectivity and, more in general, drugability properties. The case of L-glutamic acid (L-Glu, 1) is of particular importance since it is the primary excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays a critical r...
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ژورنال
عنوان ژورنال: The Journal of the Society of Chemical Industry, Japan
سال: 1963
ISSN: 0023-2734,2185-0860
DOI: 10.1246/nikkashi1898.66.10_1513